Mbtps1

Rattus norvegicus

Enables serine-type endopeptidase activity. Predicted to be involved in several processes, including lysosome organization; membrane protein intracellular domain proteolysis; and mitotic G2 DNA damage checkpoint signaling. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in Golgi stack. Predicted to be active in Golgi membrane. Human ortholog(s) of this gene implicated in spondyloepiphyseal dysplasia Kondo-Fu type. Orthologous to human MBTPS1 (membrane bound transcription factor peptidase, site 1); PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; ammonium chloride.