- TMUE_2000009859 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Is predicted to encode a protein with the following domains: Ubiquitin family; DC-UbP/UBTD2, N-terminal domain superfamily; Ubiquitin-binding domain; Ubiquitin-like domain superfamily; Ubiquitin-like domain; and DC-UbP/UBTD2, N-terminal domain.
- ktub [Search on AGR]
Drosophila melanogaster king tubby (ktub) encodes a protein that belongs to the tubby and tubby-like protein family. It functions in endocytosis of the rhodopsin encoded by ninaE, retinal degeneration upon light stimulation, and the localization of channel encoded by the channel encoded by trp in cilia.
- Tbxa2r [Search on AGR]
Mus musculus PHENOTYPE: Homozygotes for a null allele show prolonged bleeding, and altered platelet aggregation and vascular responses to TXA2, arachidonic acid and injury. Homozygotes for another null allele show splenomegaly, reduced DC-T cell adhesion, enhanced contact hypersensitivity, and cervical lymphadenopathy. [provided by MGI curators]
- Dcst2 [Search on AGR]
Rattus norvegicus Predicted to be involved in fusion of sperm to egg plasma membrane involved in single fertilization and sperm-egg recognition. Predicted to be located in membrane. Orthologous to human DCST2 (DC-STAMP domain containing 2); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A.
- Dcst1 [Search on AGR]
Rattus norvegicus Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including fusion of sperm to egg plasma membrane involved in single fertilization; negative regulation of type I interferon-mediated signaling pathway; and sperm-egg recognition. Predicted to be located in plasma membrane. Orthologous to human DCST1 (DC-STAMP domain containing 1); INTERACTS WITH 4,4'-diaminodiphenylmethane; aflatoxin B1; alpha-Zearalanol.
- Clec4m [Search on AGR]
Homo sapiens This gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. The protein is organized into four distinct domains: a C-terminal carbohydrate recognition domain, a flexible tandem-repeat neck domain of variable length, a transmembrane region and an N-terminal cytoplasmic domain involved in internalization. This gene is closely related in terms of both sequence and function to a neighboring gene, CD209 (Gene ID: 30835), also known as DC-SIGN. The two genes differ in viral recognition and expression patterns, with this gene showing high expression in endothelial cells of the liver, lymph node and placenta. Polymorphisms in the tandem repeat neck domain are associated with resistance to SARS infection. [provided by RefSeq, May 2020]