Predicted to enable inward rectifier potassium channel activity. Involved in short-term memory. Predicted to be located in plasma membrane. Predicted to be part of monoatomic ion channel complex. Expressed in HSNL; HSNR; and sensory neurons. Human ortholog(s) of this gene implicated in several diseases, including Bartter disease type 2; EAST syndrome; and Leber congenital amaurosis 16. Is an ortholog of human KCNJ10 (potassium inwardly rectifying channel subfamily J member 10); KCNJ13 (potassium inwardly rectifying channel subfamily J member 13); and KCNJ15 (potassium inwardly rectifying channel subfamily J member 15).
Enables phosphatidylinositol phosphate phosphatase activity. Acts upstream of or within with a positive effect on flagellated sperm motility. Located in several cellular components, including neuronal cell body; nucleus; and plasma membrane bounded cell projection. Expressed in PVDL and PVDR. Human ortholog(s) of this gene implicated in congenital muscular dystrophy with cataracts and intellectual disability. Is an ortholog of human INPP5J (inositol polyphosphate-5-phosphatase J) and INPP5K (inositol polyphosphate-5-phosphatase K).
Enables inward rectifier potassium channel activity. Involved in regulation of G protein-coupled receptor signaling pathway and regulation of egg-laying behavior. Located in neuron projection and neuronal cell body. Expressed in egg-laying apparatus; gonad; intestine; and neurons. Human ortholog(s) of this gene implicated in several diseases, including glucose metabolism disease (multiple); heart conduction disease (multiple); and long QT syndrome (multiple). Is an ortholog of several human genes including KCNJ2 (potassium inwardly rectifying channel subfamily J member 2); KCNJ3 (potassium inwardly rectifying channel subfamily J member 3); and KCNJ4 (potassium inwardly rectifying channel subfamily J member 4).
Predicted to enable RNA binding activity and ribosome binding activity. Predicted to contribute to translation initiation factor activity. Involved in positive regulation of apoptotic process. Located in cytoplasm. Expressed in several structures, including embryonic cell and germ line. Is an ortholog of human EIF3K (eukaryotic translation initiation factor 3 subunit K).
Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be located in plasma membrane. Expressed in K cell; K' cell; mc1; mc2; and seam cell.