- SK [Search on AGR]
Drosophila melanogaster small conductance calcium-activated potassium channel (SK) encodes a potassium channel subunit. Four SK subunits together form a voltage-independent potassium channel, which is activated by intracellular calcium levels and is required for normal photoreceptor light response. Contrary to its mammalian counterpart, Drosophila SK channel is not sensitive to apamin, at least not in photoreceptors.
- Glis1 [Search on AGR]
Homo sapiens GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).[supplied by OMIM, Mar 2008]
- Adig [Search on AGR]
Homo sapiens ADIG/SMAF1 is an adipocyte-specific protein that plays a role in adipocyte differentiation (Kim et al., 2005 [PubMed 15567149]; Hong et al., 2005 [PubMed 16132694]).[supplied by OMIM, Mar 2008]
- Cerk [Search on AGR]
Homo sapiens CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008]
- Son [Search on AGR]
Mus musculus PHENOTYPE: Homozygous null mice die before E6.5-7.5. Heterozygous mice model Zhu-Tokita-Takenouchi-Kim syndrome, with growth retardation, cognitive impairment, skeletal abnormalities, kidney agenesis, hematopoietic abnormalities including leukopenia and immunoglobulin deficiency and impaired erythropoiesis. [provided by MGI curators]
- Prt4 [Search on AGR]
Mus musculus PHENOTYPE: Prt4 and Prt5 loci control electrophoretic mobility of two esteroproteases inducible by testosterone in submandibular glands. Prt4 alleles are: a allele in DBA/2, M.m. molossinus and M.m. castaneus; b allele in C57BL/10, A/J, NMRI/F and SK/Cam. Heterozygotes have all parental bands. [provided by MGI curators]
- Es9 [Search on AGR]
Mus musculus PHENOTYPE: Five electrophoretically distinguishable alleles are: the a allele in strains NMRI, C3H and C57BL/Gr; the b allele in SK/Cam; the c allele in M. m. molossinus; the d allele in some Peru-Coppock mice; the e allele in Peru/1Fr. Heterozygotes have intermediate patterns. [provided by MGI curators]
- Es23 [Search on AGR]
Mus musculus PHENOTYPE: This carboxylesterase is active with substrates 5-bromoindoxyl acetate and alpha-naphthyl butyrate. Five electrophoretic alleles are known: a in M.m. molossinus; b in M.m. castaneus; c in C57BL/10 and most inbreds; d (null) in SK/Cam; e in M. spretus. The b allele also determines expression in lung. [provided by MGI curators]
- Asmt [Search on AGR]
Mus musculus PHENOTYPE: Pineal melatonin synthesis requires enzymes encoded by Asmt and Aanat. C57BL/6, BALB/c, AKR/J, NZB/Bl, IS/Cam, and CAST/Ei carry the a allele of Asmt and lack melatonin. SK/Cam, SF/Cam, PERU, and FDS carry the b allele and have normal melatonin levels. [provided by MGI curators]
- kcnl-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable calmodulin binding activity and small conductance calcium-activated potassium channel activity. Involved in positive regulation of egg-laying behavior. Located in neuron projection. Expressed in nervous system; seam cell; and vulval muscle. Human ortholog(s) of this gene implicated in dystonia and paranoid schizophrenia. Is an ortholog of human KCNN1 (potassium calcium-activated channel subfamily N member 1).