flp-33

Caenorhabditis elegans

Enriched in G2; W cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including mut-16; atfs-1; and etr-1 based on RNA-seq; microarray; and proteomic studies. Is affected by nine chemicals including 1-methylnicotinamide; rotenone; and D-glucose based on RNA-seq studies.

ddo-2

Caenorhabditis elegans

Enables D-aspartate oxidase activity and D-glutamate oxidase activity. Involved in aspartate catabolic process. Predicted to be located in peroxisomal matrix. Expressed in body wall musculature; intestinal cell; and pharyngeal muscle cell.

K10D6.3

Caenorhabditis elegans

Enriched in ADEshL; ADEshR; G2; W cell; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including nuo-6; etr-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; Tunicamycin; and D-glucose based on microarray and RNA-seq studies.

daao-1

Caenorhabditis elegans

Enables D-amino-acid oxidase activity. Predicted to be involved in D-amino acid catabolic process and digestion. Predicted to be located in cytoplasm. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human DDO (D-aspartate oxidase).

ddo-1

Caenorhabditis elegans

Enables D-aspartate oxidase activity; D-glutamate oxidase activity; and FAD binding activity. Predicted to be involved in D-amino acid catabolic process. Predicted to be located in peroxisomal matrix. Expressed in hypodermis and intestinal cell. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human DAO (D-amino acid oxidase).

F32D8.12

Caenorhabditis elegans

Predicted to enable D-lactate dehydrogenase (cytochrome) activity; D-lactate dehydrogenase activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in lactate catabolic process. Predicted to be located in mitochondrion. Is an ortholog of human LDHD (lactate dehydrogenase D).

cyp-14A2

Caenorhabditis elegans

Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; extrapyramidal and movement disease; and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1).

cyp-14A4

Caenorhabditis elegans

Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; extrapyramidal and movement disease; and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1).

cyp-14A1

Caenorhabditis elegans

Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; extrapyramidal and movement disease; and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1).

T10G3.3

Caenorhabditis elegans

Enriched in G2; W cell; and seam cell based on single-cell RNA-seq studies. Is affected by several genes including cyc-1; hyl-2; and qui-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including Tunicamycin; D-glucopyranose; and bisphenol S based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Abnormal cell migration protein 18-like; Fibronectin type I domain; and Phosphorylation site.