- spl [Search on AGR]
Mus musculus PHENOTYPE: This locus controls level of serotonin in plasma. C57BL/6By carries the allele for high level (1.7-2.2 micrograms/ml); BALB/cBy carries the allele for low level (0.6-0.8 micrograms/ml). [provided by MGI curators]
- HPT1 [Search on AGR]
Saccharomyces cerevisiae Dimeric hypoxanthine-guanine phosphoribosyltransferase; catalyzes the transfer of the phosphoribosyl portion of 5-phosphoribosyl-alpha-1-pyrophosphate to a purine base (either guanine or hypoxanthine) to form pyrophosphate and a purine nucleotide (either guanosine monophosphate or inosine monophosphate); mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome