rft-1

Caenorhabditis elegans

Enables riboflavin transmembrane transporter activity. Involved in embryo development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A2 (solute carrier family 52 member 2) and SLC52A3 (solute carrier family 52 member 3).

rft-2

Caenorhabditis elegans

Enables riboflavin transmembrane transporter activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A1 (solute carrier family 52 member 1); SLC52A2 (solute carrier family 52 member 2); and SLC52A3 (solute carrier family 52 member 3).

bt2

Mus musculus

PHENOTYPE: Homozygous mutants have a narrow white belt. [provided by MGI curators]

GRHL3-AS1

Homo sapiens

ASSOCIATED WITH Van der Woude Syndrome 2

paic-1

Caenorhabditis elegans

Enables identical protein binding activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase).

adss-1

Caenorhabditis elegans

Predicted to enable adenylosuccinate synthase activity. Predicted to be involved in 'de novo' AMP biosynthetic process and IMP metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ADSS1 (adenylosuccinate synthase 1).

Adamts20

Mus musculus

PHENOTYPE: Mice homozygous for spontaneous or ENU-induced mutations exhibit abnormal coat/hair pigmentation, including a typical white belt phenotype. [provided by MGI curators]

tdo-2

Caenorhabditis elegans

Predicted to enable heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in tryptophan catabolic process to acetyl-CoA. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Is an ortholog of human TDO2 (tryptophan 2,3-dioxygenase).

skc44

Mus musculus

PHENOTYPE: Some homozygous mice have a white belt that fades on ventral side, while other affected mice simply have large spots. [provided by MGI curators]

PPA39683

Pristionchus pacificus

Is predicted to encode a protein with the following domains: De-etiolated protein 1, Det1 and De-etiolated protein 1 Det1.