- spk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein serine/threonine kinase activity. Involved in embryo development. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including gonad and tail. Is an ortholog of human SRPK1 (SRSF protein kinase 1); SRPK2 (SRSF protein kinase 2); and SRPK3 (SRSF protein kinase 3).
- tsr-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in protein import into nucleus. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 2. Is an ortholog of human TNPO3 (transportin 3).
- Tnpo-SR [Search on AGR]
Drosophila melanogaster Transportin-Serine/Arginine rich (Tnpo-SR) encodes a importin-beta family protein involved in the regulation of mRNA splicing. It contributes to the import into the nucleus of serine/arginine-rich (SR) proteins, which are involved in mRNA splicing.
- SRPK [Search on AGR]
Drosophila melanogaster SR Protein Kinase (SRPK) encodes a protein involved in spindle microtubule assembly and karyosome formation in oocytes.
- Srek1 [Search on AGR]
Homo sapiens This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
- Hrc [Search on AGR]
Homo sapiens This gene encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. The protein interacts with the cytoplasmic domain of triadin, the main transmembrane protein of the junctional sarcoplasmic reticulum (SR) of skeletal muscle. The protein functions in the regulation of releasable calcium into the SR. [provided by RefSeq, Sep 2008]
- rsp-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Human ortholog(s) of this gene implicated in autism spectrum disorder and myelodysplastic syndrome. Is an ortholog of human SREK1 (splicing regulatory glutamic acid and lysine rich protein 1).
- Srprb [Search on AGR]
Homo sapiens The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane. [provided by RefSeq, Jul 2008]