ara

Drosophila melanogaster

araucan (ara) encodes a homeodomain-containing protein of the TALE subfamily and one of the three components of the Iroquois gene complex. ara product acts as a transcriptional regulator to control territorial and cell fate specification, cell sorting behaviour and pattern formation. It also plays a transcription independent cell-autonomous role in cell proliferation control.

F43B10.1

Caenorhabditis elegans

Predicted to enable protein phosphatase regulator activity. Predicted to be part of protein phosphatase type 2A complex. Is an ortholog of human PPP2R3A (protein phosphatase 2 regulatory subunit B''alpha) and PPP2R3B (protein phosphatase 2 regulatory subunit B''beta).

sto-3

Caenorhabditis elegans

Predicted to be located in plasma membrane. Expressed in RIB; ray neuron type B; and tail.

ldh-1

Caenorhabditis elegans

Enables L-lactate dehydrogenase activity. Predicted to be involved in lactate metabolic process and pyruvate metabolic process. Predicted to be located in mitochondrion. Expressed in tail. Is an ortholog of several human genes including LDHA (lactate dehydrogenase A); LDHB (lactate dehydrogenase B); and LDHC (lactate dehydrogenase C).

tbcb-1

Caenorhabditis elegans

Predicted to be located in cytoplasm and microtubule. Is an ortholog of human TBCB (tubulin folding cofactor B).

F52D10.2

Caenorhabditis elegans

Expressed in head and tail. Is an ortholog of human FAM43B (family with sequence similarity 43 member B).

srp-8

Caenorhabditis elegans

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including SERPINB1 (serpin family B member 1); SERPINB8 (serpin family B member 8); and SERPINB9 (serpin family B member 9).

Plch1

Homo sapiens

PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM, Jun 2009]

Y37E11AR.7

Caenorhabditis elegans

Predicted to be located in membrane. Is an ortholog of human FAM187B (family with sequence similarity 187 member B).

soem-1

Caenorhabditis elegans

Expressed in PQR. Is an ortholog of human SHB (SH2 domain containing adaptor protein B). Human SHB enables phosphotyrosine residue binding activity.