sw

Drosophila melanogaster

short wing (sw) encodes the non-catalytic intermediate chain subunit of the cytoplasmic dynein motor complex. It contributes to wing development, eye development, oocyte development and polarity, mitotic cell division, and neuronal transport and neurogenesis.

Plch1

Homo sapiens

PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM, Jun 2009]