Predicted to enable copper ion binding activity and superoxide dismutase activity. Predicted to be involved in removal of superoxide radicals. Expressed in amphid neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); eye disease (multiple); and glucose metabolism disease (multiple). Is an ortholog of human SOD1 (superoxide dismutase 1).
Enables superoxide dismutase activity. Involved in superoxide metabolic process. Located in extracellular space and membrane. Expressed in somatic gonad.
Is affected by several genes including etr-1; csr-1; and sod-2 based on microarray and RNA-seq studies. Is affected by four chemicals including silicon dioxide nanoparticle; paraquat; and cadmium based on microarray and RNA-seq studies.
Enriched in oocyte based on RNA-seq studies. Is affected by several genes including etr-1; sod-2; and inx-14 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies.
Enables protein homodimerization activity and superoxide dismutase activity. Involved in removal of superoxide radicals. Located in mitochondrion. Part of respiratory chain complex. Expressed in several structures, including head; intestine; pharynx; tail; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and liver disease (multiple). Is an ortholog of human SOD2 (superoxide dismutase 2).
Enables copper ion binding activity; protein homodimerization activity; and superoxide dismutase activity. Involved in regulation of brood size; regulation of vulval development; and removal of superoxide radicals. Located in cytosol and mitochondrion. Expressed in several structures, including intestinal cell; somatic gonad; and somatic nervous system. Used to study amyotrophic lateral sclerosis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); eye disease (multiple); and glucose metabolism disease (multiple). Is an ortholog of human SOD1 (superoxide dismutase 1).