- eme-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables enzyme binding activity. Predicted to be involved in double-strand break repair via break-induced replication; mitotic intra-S DNA damage checkpoint signaling; and resolution of meiotic recombination intermediates. Predicted to be located in nucleus. Predicted to be part of Holliday junction resolvase complex.
- mus-81 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables enzyme binding activity. Involved in several processes, including DNA recombination; larval development; and positive regulation of embryonic development. Predicted to be located in nucleus. Predicted to be part of Holliday junction resolvase complex. Is an ortholog of human MUS81 (MUS81 structure-specific endonuclease subunit).
- Gen [Search on AGR]
Drosophila melanogaster XPG-like endonuclease (Gen) encodes a nuclease that cuts Holliday junctions, flaps, and replication forks during DNA and replication fork repair.
- CCE1 [Search on AGR]
Saccharomyces cerevisiae Mitochondrial cruciform cutting endonuclease; cleaves Holliday junctions formed during recombination of mitochondrial DNA; CCE1 has a paralog, MRS1, that arose from the whole genome duplication
- gen-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables crossover junction DNA endonuclease activity. Involved in DNA damage response and negative regulation of nematode larval development. Predicted to be located in cytoplasm and nucleus.
- Hfm1 [Search on AGR]
Saccharomyces cerevisiae Meiosis specific DNA helicase; involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity
- Lalba [Search on AGR]
Homo sapiens This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008]