HMRA2

Saccharomyces cerevisiae

Silenced copy of a2 at HMR; similarity to Alpha2p; required along with a1p for inhibiting expression of the HO endonuclease in a/alpha HO/HO diploid cells with an active mating-type interconversion system

Ho

Drosophila melanogaster

Heme oxygenase (Ho) encodes a heme oxygenase involved in heme metabolism.

wmd

Drosophila melanogaster

wing morphogenesis defect (wmd) encodes an essential WD-repeat protein that is required for wing development and motor behavior.

nub

Drosophila melanogaster

nubbin (nub) encodes a POU/homeodomain transcription factor that is expressed in the nascent wing primordium and is required for wing formation.

ash1

Saccharomyces cerevisiae

Component of the Rpd3L histone deacetylase complex; zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate

sw

Drosophila melanogaster

short wing (sw) encodes the non-catalytic intermediate chain subunit of the cytoplasmic dynein motor complex. It contributes to wing development, eye development, oocyte development and polarity, mitotic cell division, and neuronal transport and neurogenesis.

ltl

Drosophila melanogaster

larval translucida (ltl) encodes a leucine-rich repeat protein involved in wing vein specification.

BCAS2

Drosophila melanogaster

BCAS2 (BCAS2) encodes an essential protein that regulates wing development via Delta-Notch signaling.

Irk3

Drosophila melanogaster

Inwardly rectifying potassium channel 3 (Irk3) encodes a protein involved in wing disc development.

Sdb

Drosophila melanogaster

SAXO downstream of blistered (Sdb) encodes a large protein conserved in other insects with up to 80 copies of a tandem array of a 29 amino acid repeat. Ubiquitous Sdb RNAi causes lethality and wing-specific RNAi causes wing adhesion defects.