abhd-14

Caenorhabditis elegans

Predicted to enable hydrolase activity. Predicted to be located in cytoplasm. Is an ortholog of human ABHD14B (abhydrolase domain containing 14B).

T25D3.4

Caenorhabditis elegans

Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human MFSD14A (major facilitator superfamily domain containing 14A) and MFSD14B (major facilitator superfamily domain containing 14B).

F55C10.5

Caenorhabditis elegans

Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in stomach cancer. Is an ortholog of several human genes including PPP1R14B (protein phosphatase 1 regulatory inhibitor subunit 14B); PPP1R14C (protein phosphatase 1 regulatory inhibitor subunit 14C); and PPP1R14D (protein phosphatase 1 regulatory inhibitor subunit 14D).

avr-14

Caenorhabditis elegans

Enables extracellularly glutamate-gated chloride channel activity. Involved in several processes, including locomotion involved in locomotory behavior; regulation of nematode pharyngeal pumping; and response to xenobiotic stimulus. Located in membrane. Expressed in head; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in hyperekplexia 1 and syndromic X-linked intellectual disability Pilorge type. Is an ortholog of human GLRA1 (glycine receptor alpha 1); GLRA2 (glycine receptor alpha 2); and GLRA3 (glycine receptor alpha 3).

ZK673.4

Caenorhabditis elegans

Predicted to enable metal ion binding activity.

ets-6

Caenorhabditis elegans

Predicted to be involved in negative regulation of vulval development.

glc-1

Caenorhabditis elegans

Enables extracellularly glutamate-gated chloride channel activity; glutamate binding activity; and identical protein binding activity. Involved in chloride transmembrane transport; locomotion involved in locomotory behavior; and protein complex oligomerization. Located in plasma membrane. Expressed in body wall musculature; head neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in hyperekplexia 1; hyperekplexia 2; and syndromic X-linked intellectual disability Pilorge type. Is an ortholog of human GLRA2 (glycine receptor alpha 2) and GLRA3 (glycine receptor alpha 3).

F19F10.11

Caenorhabditis elegans

Predicted to be involved in negative regulation of vulval development.

Y32B12B.4

Caenorhabditis elegans

Predicted to be involved in negative regulation of vulval development.

glc-4

Caenorhabditis elegans

Predicted to enable neurotransmitter receptor activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection; plasma membrane; and synapse. Predicted to be part of transmembrane transporter complex. Expressed in AIYL and AIYR.