K09E4.3

Caenorhabditis elegans

Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 16. Is an ortholog of human NDUFAF5 (NADH:ubiquinone oxidoreductase complex assembly factor 5).

nuaf-3

Caenorhabditis elegans

Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 18. Is an ortholog of human NDUFAF3 (NADH:ubiquinone oxidoreductase complex assembly factor 3).

B0035.15

Caenorhabditis elegans

Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 15. Is an ortholog of human NDUFAF4 (NADH:ubiquinone oxidoreductase complex assembly factor 4).

ndua-8

Caenorhabditis elegans

Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Is an ortholog of human NDUFA8 (NADH:ubiquinone oxidoreductase subunit A8).

ndub-10

Caenorhabditis elegans

Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 35. Is an ortholog of human NDUFB10 (NADH:ubiquinone oxidoreductase subunit B10).

C34E10.12

Caenorhabditis elegans

Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 34. Is an ortholog of human NDUFAF8 (NADH:ubiquinone oxidoreductase complex assembly factor 8).

Y116A8C.30

Caenorhabditis elegans

Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 10. Is an ortholog of human NDUFAF2 (NADH:ubiquinone oxidoreductase complex assembly factor 2).

nduf-9

Caenorhabditis elegans

Predicted to be involved in mitochondrial respiratory chain complex I assembly and ubiquinone-6 biosynthetic process. Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex I. Expressed in head and tail. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 26. Is an ortholog of human NDUFA9 (NADH:ubiquinone oxidoreductase subunit A9).

lpd-5

Caenorhabditis elegans

Involved in lipid storage. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in Leigh disease and nuclear type mitochondrial complex I deficiency 1. Is an ortholog of human NDUFS4 (NADH:ubiquinone oxidoreductase subunit S4).

rpoa-1

Caenorhabditis elegans

Predicted to enable DNA binding activity and DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase I activity. Predicted to be involved in transcription by RNA polymerase I. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex. Human ortholog(s) of this gene implicated in acrofacial dysostosis Cincinnati type and hypomyelinating leukodystrophy. Is an ortholog of human POLR1A (RNA polymerase I subunit A).