rod-1

Caenorhabditis elegans

Enables protein domain specific binding activity. Involved in several processes, including chromosome organization; positive regulation of kinetochore assembly; and regulation of cell cycle process. Part of RZZ complex. Is an ortholog of human KNTC1 (kinetochore associated 1).

R07E3.1

Caenorhabditis elegans

Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSW (cathepsin W).

C33A11.2

Caenorhabditis elegans

Predicted to be located in membrane. Expressed in several structures, including CAN; gonad; head; pharyngeal cell; and tail. Human ortholog(s) of this gene implicated in cone-rod dystrophy. Is an ortholog of human DRAM2 (DNA damage regulated autophagy modulator 2).

R09F10.1

Caenorhabditis elegans

Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSW (cathepsin W).

Y51A2D.8

Caenorhabditis elegans

Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSW (cathepsin W).

ubc-16

Caenorhabditis elegans

Predicted to enable ubiquitin conjugating enzyme activity. Involved in protein ubiquitination. Predicted to be located in nucleus. Expressed in germ line and oocyte. Is an ortholog of human UBE2W (ubiquitin conjugating enzyme E2 W).

npr-32

Caenorhabditis elegans

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of human NPBWR1 (neuropeptides B and W receptor 1).

CFAP418-AS1

Homo sapiens

ASSOCIATED WITH Bardet-Biedl syndrome 21; cone-rod dystrophy; cone-rod dystrophy 16; INTERACTS WITH aflatoxin B1; benzo[a]pyrene; bisphenol A

Sag

Mus musculus

PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormalities in retinal rod cell outer segment morphology and rod electrophysiology. [provided by MGI curators]

Y18H1A.11

Caenorhabditis elegans

Predicted to enable choline-phosphate cytidylyltransferase activity and phosphatidylcholine binding activity. Predicted to be involved in CDP-choline pathway. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy and spondylometaphyseal dysplasia with cone-rod dystrophy. Is an ortholog of human PCYT1A (phosphate cytidylyltransferase 1A, choline) and PCYT1B (phosphate cytidylyltransferase 1B, choline).