Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate determination. Located in nucleus. Expressed in E lineage cell.
Enables carboxylesterase activity. Involved in cellular catabolic process. Located in peroxisome. Expressed in pharynx. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1).
Predicted to enable GTPase activity. Involved in lipid storage and lysosome organization. Located in gut granule membrane. Expressed in intestine. Is an ortholog of human RAB32 (RAB32, member RAS oncogene family).
Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in gut granule assembly and lipid storage. Located in gut granule membrane. Expressed in AWAL and AWAR. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of human ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4).
Predicted to enable several functions, including ATP binding activity; helicase activity; and nucleic acid binding activity. Predicted to be located in cytoplasm. Is an ortholog of human DDX60 (DExD/H-box helicase 60) and DDX60L (DExD/H-box 60 like).
Predicted to enable box H/ACA snoRNA binding activity. Predicted to be involved in snoRNA guided rRNA pseudouridine synthesis. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex. Is an ortholog of human GAR1 (GAR1 ribonucleoprotein).