- SEI1 [Search on AGR]
Saccharomyces cerevisiae Seipin involved in lipid droplet (LD) assembly; controls lipid particle morphology, number, and size; promotes initiation of LD formation on the ER; ensures that LDs bud from the ER towards the cytosolic side of the membrane; forms a complex with Ldb16p at ER-LD contact sites, stabilizing these sites; null mutants have localized accumulation of phosphatidic acid (PA) marker proteins; BSCL2, human homolog implicated in congenital lipodystrophy, complements yeast null mutant
- LDH1 [Search on AGR]
Saccharomyces cerevisiae Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif)
- LPL1 [Search on AGR]
Saccharomyces cerevisiae Phospholipase; contains lipase specific GXSXG motif; maintains lipid droplet (LD) morphology; induced by transcription factor Rpn4p; protein abundance increases in response to DNA replication stress
- LDB16 [Search on AGR]
Saccharomyces cerevisiae Protein involved in lipid droplet (LD) assembly; forms a complex with Sei1p at ER-LD contact sites, stabilizing contact sites; ensures that LDs bud from the ER towards the cytosolic side of the membrane; null mutants have decreased net negative cell surface charge and localized accumulation of phosphatidic acid (PA) marker proteins; GFP-fusion protein expression is induced in response to MMS; null mutant can be complemented by the human seipin, BSCL2
- EAT1 [Search on AGR]
Saccharomyces cerevisiae Ethanol acetyltransferase; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion
- DOS2 [Search on AGR]
Saccharomyces cerevisiae Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
- MIN4 [Search on AGR]
Saccharomyces cerevisiae Mitochondrial protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria
- YBL086C [Search on AGR]
Saccharomyces cerevisiae Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
- YJR154W [Search on AGR]
Saccharomyces cerevisiae Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm