- irk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables inward rectifier potassium channel activity. Involved in regulation of G protein-coupled receptor signaling pathway and regulation of egg-laying behavior. Located in neuron projection and neuronal cell body. Expressed in egg-laying apparatus; gonad; intestine; and neurons. Human ortholog(s) of this gene implicated in several diseases, including glucose metabolism disease (multiple); heart conduction disease (multiple); and long QT syndrome (multiple). Is an ortholog of several human genes including KCNJ2 (potassium inwardly rectifying channel subfamily J member 2); KCNJ3 (potassium inwardly rectifying channel subfamily J member 3); and KCNJ4 (potassium inwardly rectifying channel subfamily J member 4).
- npr-41 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of human GPR142 (G protein-coupled receptor 142).
- mth-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in X-linked congenital bilateral absence of vas deferens and vibratory urticaria. Is an ortholog of human ADGRE2 (adhesion G protein-coupled receptor E2); ADGRG2 (adhesion G protein-coupled receptor G2); and ADGRG7 (adhesion G protein-coupled receptor G7).