T13G4.4

Caenorhabditis elegans

Predicted to enable S-adenosylmethionine-homocysteine S-methyltransferase activity. Predicted to be involved in S-methylmethionine cycle and methionine biosynthetic process.

fred

Drosophila melanogaster

friend of echinoid (fred) encodes a protein involved in cuticle biosynthesis and ommatidial rotation.

gst-34

Caenorhabditis elegans

Predicted to enable glutathione transferase activity. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).

W10C8.4

Caenorhabditis elegans

Predicted to enable glutathione transferase activity. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).

gst-35

Caenorhabditis elegans

Predicted to enable glutathione transferase activity. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).

msra-1

Caenorhabditis elegans

Enables L-methionine:thioredoxin-disulfide S-oxidoreductase activity and peptide-methionine (S)-S-oxide reductase activity. Predicted to be involved in cellular response to oxidative stress. Predicted to be located in cytoplasm. Expressed in hypodermis and neurons. Is an ortholog of human MSRA (methionine sulfoxide reductase A).

slc-25A26

Caenorhabditis elegans

Enables S-adenosyl-L-methionine transmembrane transporter activity. Involved in mitochondrial S-adenosyl-L-methionine transmembrane transport. Located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 28. Is an ortholog of human SLC25A26 (solute carrier family 25 member 26).

Fhe

Mus musculus

PHENOTYPE: This locus controls development of erythroblastosis induced by helper virus component of Friend NB-tropic virus. The r allele determines resistance in C57BL/6 and B10.D2 strains; the s allele determines susceptibility in BALB/c. F1 mice are resistant. [provided by MGI curators]

Mst1r

Mus musculus

PHENOTYPE: This locus controls susceptibility to splenomegaly or spleen focus formation induced by inoculation with Friend leukemia virus. [provided by MGI curators]

ahcy-1

Caenorhabditis elegans

Predicted to enable adenosylhomocysteinase activity. Predicted to be involved in S-adenosylhomocysteine catabolic process and S-adenosylmethionine cycle. Predicted to be located in cytosol. Expressed in head. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm and hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase. Is an ortholog of human AHCY (adenosylhomocysteinase).