C55A6.10

Caenorhabditis elegans

Located in striated muscle dense body. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 66. Is an ortholog of human FERRY3 (FERRY endosomal RAB5 effector complex subunit 3).

Ferry3

Rattus norvegicus

Involved in regulation of mast cell degranulation. Located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 66. Orthologous to human FERRY3 (FERRY endosomal RAB5 effector complex subunit 3); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; Brodifacoum.

Sema7a

Homo sapiens

This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]