- cdk-12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in nematode larval development. Located in euchromatin. Expressed in several structures, including germ line and head. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; carcinoma (multiple); and congenital heart defects, dysmorphic facial features, and intellectual developmental disorder. Is an ortholog of human CDK13 (cyclin dependent kinase 13).
- moct [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a spontaneous allele exhibit abnormal lens features including bilateral cataracts. [provided by MGI curators]
- Scn3b [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a knock-out allele exhibit a ventricular arrhythmogenic phenotype with abnormal heart electrocardiography waveform features and sodium channel function. [provided by MGI curators]
- Alpk3 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a gene-trappped allele exhibit altered cardiomyocyte architecture and develop a non-progressive cardiomyopathy that presents features of both hypertrophic and dilated forms of cardiomyopathy, [provided by MGI curators]
- Rspo1 [Search on AGR]
Mus musculus PHENOTYPE: Homozygous inactivation of this gene leads to abnormal ovarian development and masculinized features including pseudohermaphroditism in genital ducts, depletion of fetal oocytes, male-like vascularization, and ectopic testosterone production in the ovaries. [provided by MGI curators]
- Scrt1 [Search on AGR]
Homo sapiens This gene encodes a C2H2-type zinc finger transcriptional repressor that binds to E-box motifs. The encoded protein may promote neural differention and may be involved in cancers with neuroendocrine features. [provided by RefSeq, Jul 2013]
- Gcsh [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size and fail to develop beyond early post-implantation stages with no recognizable embryonic features such as somites or cranial neural folds. [provided by MGI curators]
- Clcn6 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired nociception, mild behavioral abnormalities, and a progressive neuropathy of the central and peripheral nervous systems with features of neuronal ceroid lipofuscinosis (a lysosomal storage disease). [provided by MGI curators]
- Hyal2 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a knock-out allele exhibit preweaning lethality, poor survival, craniofacial defects including submucosal cleft palate, and mild anemia. Incompletely penetrant features include cor triatriatum sinister and hearing loss. [provided by MGI curators]