rft-1

Caenorhabditis elegans

Enables riboflavin transmembrane transporter activity. Involved in embryo development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A2 (solute carrier family 52 member 2) and SLC52A3 (solute carrier family 52 member 3).

Y53F4B.12

Caenorhabditis elegans

Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-arginine import across plasma membrane and L-ornithine transmembrane transport. Predicted to be located in plasma membrane.

rft-2

Caenorhabditis elegans

Enables riboflavin transmembrane transporter activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A1 (solute carrier family 52 member 1); SLC52A2 (solute carrier family 52 member 2); and SLC52A3 (solute carrier family 52 member 3).

F08F3.4

Caenorhabditis elegans

Predicted to enable L-threonine 3-dehydrogenase activity. Involved in innate immune response. Is an ortholog of human TDH (L-threonine dehydrogenase (pseudogene)).

C15B12.1

Caenorhabditis elegans

Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be located in peroxisome. Is an ortholog of human PIPOX (pipecolic acid and sarcosine oxidase).

C15B12.8

Caenorhabditis elegans

Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be located in peroxisome. Is an ortholog of human PIPOX (pipecolic acid and sarcosine oxidase).

irld-26

Caenorhabditis elegans

Is affected by several genes including drh-3; sir-2.1; and lin-14 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L domain; Receptor L-domain; SPS2 domain-containing protein; and Receptor L-domain superfamily.

Y51H7C.9

Caenorhabditis elegans

Predicted to enable L-serine ammonia-lyase activity and threonine deaminase activity. Predicted to be involved in L-serine catabolic process; isoleucine biosynthetic process; and threonine catabolic process.

srdh-1

Caenorhabditis elegans

Predicted to enable L-serine ammonia-lyase activity and threonine deaminase activity. Predicted to be involved in L-serine catabolic process; isoleucine biosynthetic process; and threonine catabolic process.

irld-51

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by hpl-2 and csr-1 based on tiling array and RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L domain; Receptor L-domain; SPS2 domain-containing protein; and Receptor L-domain superfamily.