Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Predicted to be located in cytoplasm. Is an ortholog of C. elegans eng-1.
Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Predicted to be located in cytoplasm. Is an ortholog of C. elegans eng-1.
Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Predicted to be located in cytoplasm. Is an ortholog of C. elegans eng-1.
Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Predicted to be located in cytoplasm. Is an ortholog of C. elegans eng-1.
Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Predicted to be located in cytoplasm. Is an ortholog of C. elegans eng-1.
Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Predicted to be located in cytoplasm. Is an ortholog of C. elegans eng-1.
PHENOTYPE: AKR/J, C57BL/10, CBA/J, C3H/HeJ, C58/J, MA/My, MRL/Mp, RF/J, and B10.A(5R) strains carry the dominant b allele that allows expression of I-Jk antigen when in combination with H2k. CE/J and B10.A(3R) carry the a allele that does not allow expression of I-Jk in combination with H2k. [provided by MGI curators]
Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Predicted to be located in cytoplasm. Is an ortholog of C. elegans F01F1.15 and eng-1.
Enables type II transforming growth factor beta receptor binding activity. Involved in several processes, including cellular response to mechanical stimulus; positive regulation of collagen biosynthetic process; and positive regulation of macromolecule metabolic process. Located in cell surface and extracellular space. Used to study congestive heart failure; pre-eclampsia; and renal fibrosis. Biomarker of cholestasis; congestive heart failure; hepatocellular carcinoma; hypertension (multiple); and renal fibrosis. Human ortholog(s) of this gene implicated in arteriovenous malformation; arteriovenous malformations of the brain; breast cancer; hereditary hemorrhagic telangiectasia; and intracranial aneurysm. Orthologous to human ENG (endoglin); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 4-amino-2,6-dinitrotoluene.