- slf [Search on AGR]
Drosophila melanogaster schlaff (slf) encodes a chitin binding protein involved in wing formation and the substrate for the product of Tg.
- Lipg [Search on AGR]
Homo sapiens The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008]
- enu67 [Search on AGR]
Mus musculus PHENOTYPE: Mice with at least one copy of an ENU-induced allele exhibit slower weight gain than in Tg(Thy1-MAPT*K369I)K3Gotz mice. [provided by MGI curators]
- enu164 [Search on AGR]
Mus musculus PHENOTYPE: Mice with at least one copy of an ENU-induced allele exhibit partially rescue motor defects associated with Tg(Thy1-MAPT*K369I)K3Gotz. [provided by MGI curators]
- Hunk [Search on AGR]
Mus musculus PHENOTYPE: Mutations in this gene result in no abnormal phenotype, however in combination with Tg(MMTV-Myc)Led mice, metastatic potential of mammary tumors is decreased. [provided by MGI curators]
- Eig71Ee [Search on AGR]
Drosophila melanogaster Ecdysone-induced gene 71Ee (Eig71Ee) encodes a protein of unknown function. It is expressed in larvae in both salivary glue and the hemolymph clot, where it is a substrate of the product of Tg.
- Supt4a [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality at E7.5. Mice heterozygous for a knock-out allele partially suppress the motor defects and premature death associated with Tg(HDexon1)62Gpb. [provided by MGI curators]
- Tm6sf2 [Search on AGR]
Mus musculus PHENOTYPE: Homozygotes for a null allele show hepatosteatosis, hypocholesterolemia, increased serum alanine transaminase level, reduced VLDL-TG secretion, small VLDL particles, and lipid accumulation in enterocytes. Homozygotes for another null allele show reduced total cholesterol and LDL cholesterol levels. [provided by MGI curators]
- Tg [Search on AGR]
Drosophila melanogaster Transglutaminase (Tg) encodes an enzyme that catalyzes the isopeptide bond formation of epsilon-(gamma-glutamyl)lysine bonds in a Ca2+-dependent manner. It maintains the homeostasis of gut microbiota and promotes peritrophic matrix formation, as well as mediating cuticular morphogenesis and haemolymph coagulation.
- SAH1 [Search on AGR]
Saccharomyces cerevisiae S-adenosyl-L-homocysteine hydrolase; catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor; regulates cellular lipid homoeostasis by regulating phosphatidylcholine(PC)synthesis and triacylglycerol (TG) levels