slc-25A26

Caenorhabditis elegans

Enables S-adenosyl-L-methionine transmembrane transporter activity. Involved in mitochondrial S-adenosyl-L-methionine transmembrane transport. Located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 28. Is an ortholog of human SLC25A26 (solute carrier family 25 member 26).

msra-1

Caenorhabditis elegans

Enables L-methionine:thioredoxin-disulfide S-oxidoreductase activity and peptide-methionine (S)-S-oxide reductase activity. Predicted to be involved in cellular response to oxidative stress. Predicted to be located in cytoplasm. Expressed in hypodermis and neurons. Is an ortholog of human MSRA (methionine sulfoxide reductase A).

W03G11.3

Caenorhabditis elegans

Predicted to enable alpha-L-fucosidase activity. Predicted to be involved in fucose metabolic process and glycoside catabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in fucosidosis; type 1 diabetes mellitus; and type 2 diabetes mellitus. Is an ortholog of human FUCA1 (alpha-L-fucosidase 1) and FUCA2 (alpha-L-fucosidase 2).

ahcy-1

Caenorhabditis elegans

Predicted to enable adenosylhomocysteinase activity. Predicted to be involved in S-adenosylhomocysteine catabolic process and S-adenosylmethionine cycle. Predicted to be located in cytosol. Expressed in head. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm and hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase. Is an ortholog of human AHCY (adenosylhomocysteinase).

basl-1

Caenorhabditis elegans

Predicted to enable aromatic-L-amino-acid decarboxylase activity. Predicted to be involved in catecholamine metabolic process and serotonin biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including aromatic L-amino acid decarboxylase deficiency; hyperinsulinism; and nicotine dependence. Is an ortholog of human DDC (dopa decarboxylase).

Y62E10A.13

Caenorhabditis elegans

Predicted to enable L-phosphoserine phosphatase activity and magnesium ion binding activity. Predicted to be involved in L-serine biosynthetic process. Predicted to be located in cytoplasm. Expressed in head. Human ortholog(s) of this gene implicated in PSPH deficiency. Is an ortholog of human PSPH (phosphoserine phosphatase).

slc-25A18.2

Caenorhabditis elegans

Predicted to enable L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport; aspartate transmembrane transport; and malate-aspartate shuttle. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 3. Is an ortholog of human SLC25A18 (solute carrier family 25 member 18) and SLC25A22 (solute carrier family 25 member 22).

D2023.4

Caenorhabditis elegans

Enables N-acetyltransferase activity. Is an ortholog of human SAT1 (spermidine/spermine N1-acetyltransferase 1) and SAT2 (spermidine/spermine N1-acetyltransferase family member 2).

Y53F4B.12

Caenorhabditis elegans

Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-arginine import across plasma membrane and L-ornithine transmembrane transport. Predicted to be located in plasma membrane.

glt-7

Caenorhabditis elegans

Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in plasma membrane. Expressed in excretory canal. Human ortholog(s) of this gene implicated in Huntington's disease; amyotrophic lateral sclerosis; and developmental and epileptic encephalopathy 41. Is an ortholog of human SLC1A2 (solute carrier family 1 member 2).