Pgm5 [Search on AGR]
Homo sapiens Phosphoglucomutases (EC 5.2.2.2.), such as PGM5, are phosphotransferases involved in interconversion of glucose-1-phosphate and glucose-6-phosphate. PGM activity is essential in formation of carbohydrates from glucose-6-phosphate and in formation of glucose-6-phosphate from galactose and glycogen (Edwards et al., 1995 [PubMed 8586438]).[supplied by OMIM, Mar 2008]
Agrp [Search on AGR]
Rattus norvegicus Predicted to enable neuropeptide hormone activity and type 1 melanocortin receptor binding activity. Involved in several processes, including adult feeding behavior; neuropeptide signaling pathway; and positive regulation of feeding behavior. Located in extracellular space and neuronal cell body. Biomarker of obesity and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human AGRP (agouti related neuropeptide); PARTICIPATES IN altered melanocortin system pathway; melanocortin system pathway; obesity pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-deoxy-D-glucose; AM-251.