- tdo-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in tryptophan catabolic process to acetyl-CoA. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Is an ortholog of human TDO2 (tryptophan 2,3-dioxygenase).
- larp-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in positive regulation of translation. Predicted to be located in cytoplasmic stress granule and cytosol. Expressed in PVDL; PVDR; and neurons. Is an ortholog of human LARP4 (La ribonucleoprotein 4) and LARP4B (La ribonucleoprotein 4B).
- larp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables poly(G) binding activity and poly(U) RNA binding activity. Predicted to be involved in positive regulation of translation. Located in P-body. Expressed in germ line; head; and tail. Is an ortholog of human LARP1 (La ribonucleoprotein 1, translational regulator) and LARP1B (La ribonucleoprotein 1B).
- PGRP-LA [Search on AGR]
Drosophila melanogaster Peptidoglycan recognition protein LA (PGRP-LA) encodes a protein implicated in the regulation of the immune deficiency pathway in some epithelia.
- paic-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables identical protein binding activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase).
- adss-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable adenylosuccinate synthase activity. Predicted to be involved in 'de novo' AMP biosynthetic process and IMP metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ADSS1 (adenylosuccinate synthase 1).
- ssb-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable mRNA binding activity. Predicted to be involved in positive regulation of translation and tRNA processing. Predicted to be located in cytoplasmic stress granule; cytosol; and nucleus. Predicted to be part of ribonucleoprotein complex. Expressed in head and tail. Is an ortholog of human SSB (small RNA binding exonuclease protection factor La).
- Larp1b [Search on AGR]
Homo sapiens This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined. [provided by RefSeq, Jun 2013]