Ea2

Mus musculus

PHENOTYPE: This locus regulates a cellular antigen detected on erythrocytes, spleen, thymus, liver, lung, brain, and testis. The a allele determines Ea2.1 antigen in F/St, RF/J, FM/Un and RIII strains; the b allele determines Ea2.2 antigen in most other strains. [provided by MGI curators]

HAC1

Saccharomyces cerevisiae

Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog); regulates unfolded protein response via UPRE binding and membrane biogenesis; translation initiation repressed under non-stress conditions by un-spliced intron that interacts with 5'-UTR; under ER stress Ire1p nuclease cleaves out inhibitory intron and triggers efficient Hac1p translation; two functional forms of Hac1p are produced; protein abundance increases in response to DNA replication stress

Airn

Homo sapiens

Both spliced and un-spliced long non-coding RNAs are transcribed from this gene. This gene overlaps on the opposite strand the second intron of the insulin-like growth factor 2 receptor gene; a CpG island associated with the second intron denotes an active promoter that drives the expression of this gene. The related mouse gene is responsible for silencing the insulin-like growth factor 2 receptor gene and flanking genes in the imprinted gene cluster of mice. This gene may be expressed in Wilms tumors. [provided by RefSeq, Feb 2013]