dao-4

Caenorhabditis elegans

Involved in collagen and cuticulin-based cuticle development. Predicted to be located in extracellular region and nucleus. Expressed in hyp7 syncytium and seam cell.

dao-5

Caenorhabditis elegans

Enables RNA polymerase I core binding activity and rDNA binding activity. Involved in several processes, including determination of adult lifespan; insulin receptor signaling pathway; and nucleolar large rRNA transcription by RNA polymerase I. Located in nucleolus and nucleoplasm. Expressed in germline precursor cell; gonadal sheath cell; hypodermis; and somatic cell. Is an ortholog of human NOLC1 (nucleolar and coiled-body phosphoprotein 1).

dao-3

Caenorhabditis elegans

Predicted to enable methenyltetrahydrofolate cyclohydrolase activity and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in tetrahydrofolate interconversion. Predicted to be located in cytosol. Is an ortholog of human MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase).

dao-6

Caenorhabditis elegans

Enriched in several structures, including CEPsoDL; arcade cell; excretory cell; head mesodermal cell; and pharyngeal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including numr-2; numr-1; and atfs-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Cadmium Chloride; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies.

Cbr-dao-4

Caenorhabditis briggsae

Is an ortholog of C. elegans dao-4. In C. elegans, dao-4 is involved in collagen and cuticulin-based cuticle development.

Cre-dao-4

Caenorhabditis remanei

Is an ortholog of C. elegans dao-4. In C. elegans, dao-4 is involved in collagen and cuticulin-based cuticle development.

Cbn-dao-4

Caenorhabditis brenneri

Is an ortholog of C. elegans dao-4. In C. elegans, dao-4 is involved in collagen and cuticulin-based cuticle development.

Cjp-dao-4

Caenorhabditis japonica

Is an ortholog of C. elegans dao-4. In C. elegans, dao-4 is involved in collagen and cuticulin-based cuticle development.

dao-2

Caenorhabditis elegans

Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including fzo-1; myrf-1; and numr-2 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-nine chemicals including methylmercury hydroxide; 1-methylnicotinamide; and manganese chloride based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module.

Cbr-dao-6

Caenorhabditis briggsae

Is an ortholog of C. elegans dao-6.