- jhamt [Search on AGR]
Drosophila melanogaster juvenile hormone acid methyltransferase (jhamt) encodes an enzyme that catalyzes (2E, 6E)farnesoate/ Juvenile hormone (JH) acid methylation to produce JH bisepoxide in the corpora allata. Loss of jhamt produces a delayed wandering larval stage and decreased female fecundity.
- gcna-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables SUMO polymer binding activity. Involved in meiotic chromosome segregation and protein-DNA covalent cross-linking repair. Located in PML body and condensed chromosome. Expressed in Z2; Z3; and germ cell. Human ortholog(s) of this gene implicated in spermatogenic failure. Is an ortholog of human GCNA (germ cell nuclear acidic peptidase).
- Xrcc2 [Search on AGR]
Drosophila melanogaster X-ray repair cross complementing 2 (Xrcc2) encodes a protein involved in DNA repair.
- Dclre1b [Search on AGR]
Homo sapiens DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM, Mar 2008]