cox-6C

Caenorhabditis elegans

Predicted to be located in mitochondrial inner membrane. Expressed in several structures, including body wall musculature; coelomocyte; pharynx; spermatheca; and vulva.

cox-15

Caenorhabditis elegans

Predicted to enable oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme A biosynthetic process. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Leigh disease; hypertrophic cardiomyopathy; and mitochondrial complex IV deficiency nuclear type 6. Is an ortholog of human COX15 (cytochrome c oxidase assembly homolog COX15).

cox-17

Caenorhabditis elegans

Predicted to enable copper chaperone activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human COX17 (cytochrome c oxidase copper chaperone COX17).

cox-10

Caenorhabditis elegans

Predicted to enable protoheme IX farnesyltransferase activity. Predicted to be involved in heme A biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 3. Is an ortholog of human COX10 (cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10).

cox-11

Caenorhabditis elegans

Predicted to enable copper ion binding activity. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 23. Is an ortholog of human COX11 (cytochrome c oxidase copper chaperone COX11).

cox-4

Caenorhabditis elegans

Predicted to enable oxidoreductase activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 16. Is an ortholog of human COX4I1 (cytochrome c oxidase subunit 4I1) and COX4I2 (cytochrome c oxidase subunit 4I2).

cox-5A

Caenorhabditis elegans

Predicted to enable metal ion binding activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 20. Is an ortholog of human COX5A (cytochrome c oxidase subunit 5A).

cox-6A

Caenorhabditis elegans

Predicted to enable enzyme regulator activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate D and mitochondrial complex IV deficiency nuclear type 18. Is an ortholog of human COX6A2 (cytochrome c oxidase subunit 6A2).

cox-14

Caenorhabditis elegans

Predicted to be located in membrane.

cox-16

Caenorhabditis elegans

Involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 22. Is an ortholog of human COX16 (cytochrome c oxidase assembly factor COX16).