- fecl-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ferrochelatase activity. Predicted to be involved in heme biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in colon adenocarcinoma; cutaneous porphyria; and erythropoietic protoporphyria. Is an ortholog of human FECH (ferrochelatase).
- chaf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in nucleosome assembly. Predicted to be located in nucleus. Predicted to be part of CAF-1 complex. Human ortholog(s) of this gene implicated in several diseases, including colon cancer; neuroblastoma; and systemic lupus erythematosus. Is an ortholog of human CHAF1A (chromatin assembly factor 1 subunit A).
- pfas-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable phosphoribosylformylglycinamidine synthase activity. Predicted to be involved in purine nucleotide biosynthetic process. Predicted to be located in cytoplasm. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in colon adenocarcinoma; hepatocellular carcinoma; and renal cell carcinoma. Is an ortholog of human PFAS (phosphoribosylformylglycinamidine synthase).
- Habp4 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a null allele exhibit increased proliferation of cells in the bottom of the colon crypts and show increased colon tumor development following chemical induction. [provided by MGI curators]
- Rmc1 [Search on AGR]
Homo sapiens This gene encodes a colon cancer associated protein. [provided by RefSeq, Jan 2013]
- hst-3.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Expressed in epithelial cell; hypodermis; neurons; and vulva. Human ortholog(s) of this gene implicated in several diseases, including colon cancer; hereditary angioedema; and lung non-small cell carcinoma. Is an ortholog of human HS3ST2 (heparan sulfate-glucosamine 3-sulfotransferase 2).
- Akr1b8 [Search on AGR]
Mus musculus PHENOTYPE: Mice with a knock-out allele exhibit shorter colon crypts, reduced proliferation and maturation of crypt cells, elevated levels of cytokines in the colon mucosa and increased susceptibility to induced colitis and colitis-associated tumorigenesis. [provided by MGI curators]
- Ttll3 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a knock-out allele exhibit a reduced number of primary cilia in colon epithelia accompanied by an increased rate of cell division which is compensated by faster tissue turnover in the colon. Mice exhibit increased incidence of colon tumors by chemical induction. Retinal photoreceptor connecting cilia are also affected, resulting in progressive degeneration of the photoreceptors. [provided by MGI curators]
- HNF1A-AS1 [Search on AGR]
Homo sapiens ASSOCIATED WITH colon cancer; stomach cancer; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; benzo[a]pyrene