rpoa-2

Caenorhabditis elegans

Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and ribonucleoside binding activity. Predicted to contribute to RNA polymerase I activity. Predicted to be involved in transcription by RNA polymerase I. Located in nucleolus. Expressed in several structures, including intestine. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Is an ortholog of human POLR1B (RNA polymerase I subunit B).

K06A9.1

Caenorhabditis elegans

Predicted to be located in membrane.

rpac-19

Caenorhabditis elegans

Predicted to enable protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase III and transcription elongation by RNA polymerase I. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex and RNA polymerase III complex. Used to study obesity. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 2. Is an ortholog of human POLR1D (RNA polymerase I and III subunit D).

rpac-40

Caenorhabditis elegans

Predicted to enable DNA-directed 5'-3' RNA polymerase activity and protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase I and transcription by RNA polymerase III. Predicted to be part of RNA polymerase I complex and RNA polymerase III complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 3 and hypomyelinating leukodystrophy 11. Is an ortholog of human POLR1C (RNA polymerase I and III subunit C).

tif-1A

Caenorhabditis elegans

Predicted to enable RNA polymerase I core binding activity and RNA polymerase I general transcription initiation factor activity. Predicted to be involved in transcription initiation at RNA polymerase I promoter. Predicted to be located in nucleus. Is an ortholog of human RRN3 (RRN3 homolog, RNA polymerase I transcription factor).

Polr1B

Rattus norvegicus

Contributes to DNA-directed 5'-3' RNA polymerase activity. Involved in rRNA transcription. Part of RNA polymerase I complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Orthologous to human POLR1B (RNA polymerase I subunit B); PARTICIPATES IN RNA polymerase I transcription pathway; purine metabolic pathway; pyrimidine metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

rpoa-49

Caenorhabditis elegans

Predicted to enable DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly and transcription elongation by RNA polymerase I. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I complex. Is an ortholog of human POLR1E (RNA polymerase I subunit E).

F23H11.2

Caenorhabditis elegans

Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly and nucleolar large rRNA transcription by RNA polymerase I. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I core factor complex and RNA polymerase transcription factor SL1 complex.

rpoa-12

Caenorhabditis elegans

Predicted to enable DNA-directed 5'-3' RNA polymerase activity; nucleic acid binding activity; and zinc ion binding activity. Predicted to contribute to RNA polymerase I activity. Predicted to be involved in termination of RNA polymerase I transcription. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex. Is an ortholog of human POLR1H (RNA polymerase I subunit H).

Y48E1B.3

Caenorhabditis elegans

Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly. Predicted to be located in fibrillar center.