tol-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]

Caenorhabditis elegans

Predicted to enable signaling receptor activity. Involved in defense response to Gram-negative bacterium and embryo development. Predicted to be located in extracellular matrix and extracellular space. Expressed in neurons. Is an ortholog of several human genes including CHAD (chondroadherin); ELFN2 (extracellular leucine rich repeat and fibronectin type III domain containing 2); and TRIL (TLR4 interactor with leucine rich repeats).

Chad [Search on AGR]

Rattus norvegicus

Involved in cartilage condensation. Predicted to be located in membrane. Predicted to be active in extracellular matrix and extracellular space. Orthologous to human CHAD (chondroadherin); PARTICIPATES IN cell-extracellular matrix signaling pathway; INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.