Igk-Ef2 [Search on AGR]
Mus musculus PHENOTYPE: Strain variation is seen by isoelectric focusing: BALB/c, AKR and C57BL/6 (a allele) display bands; NZB, BDP, CE, I/Ln, P/J and C58 (b allele) do not. DNA analysis with a V-kappa1A probe divide b allele strains: BDP, CE, I/Ln and P/J show the same BamHI bands as a allele strains; NZB and C58 do not. [provided by MGI curators]
Phka1 [Search on AGR]
Mus musculus PHENOTYPE: PHK activity is nearly absent in I/Ln skeletal muscle and reduced in brain, heart and kidney. The I-allele sequence is known to have a single nucleotide insertion (frameshift). A different allele in strain V reduces PHK activity to 25% and is dominant tonormal and I-strain alleles. [provided by MGI curators]
Trip12 [Search on AGR]
Rattus norvegicus Predicted to enable nuclear thyroid hormone receptor binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including chromatin remodeling; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein polyubiquitination. Predicted to be located in nucleoplasm. Predicted to be active in nuclear speck. Human ortholog(s) of this gene implicated in Clark-Baraitser syndrome. Orthologous to human TRIP12 (thyroid hormone receptor interactor 12); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.