- Fcmr [Search on AGR]
Homo sapiens Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010]
- Fcgr2al1 [Search on AGR]
Rattus norvegicus Predicted to be involved in Fc-gamma receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to human FCGR2A (Fc gamma receptor IIa) and FCGR2B (Fc gamma receptor IIb).
- F52E1.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Expressed in amphid sheath cell and phasmid sheath cell. Human ortholog(s) of this gene implicated in several diseases, including acquired immunodeficiency syndrome; bronchopulmonary dysplasia; and tuberculosis (multiple). Is an ortholog of several human genes including ASGR1 (asialoglycoprotein receptor 1); CD209 (CD209 molecule); and FCER2 (Fc epsilon receptor II).
- LOC134481532 [Search on AGR]
Rattus norvegicus Predicted to be involved in Fc-gamma receptor signaling pathway. Predicted to be located in plasma membrane.
- Fcrlb [Search on AGR]
Homo sapiens FCRL2 belongs to the Fc receptor family. Fc receptors are involved in phagocytosis, antibody-dependent cell cytotoxicity, immediate hypersensitivity, and transcytosis of immunoglobulins via their ability to bind immunoglobulin (Ig) constant regions (Chikaev et al., 2005 [PubMed 15676285]).[supplied by OMIM, Mar 2008]
- Fcrl1 [Search on AGR]
Rattus norvegicus Predicted to be located in membrane. Orthologous to human FCRL1 (Fc receptor like 1); INTERACTS WITH bisphenol A; Cuprizon.
- FCGR1CP [Search on AGR]
Homo sapiens The gene represents one of three related immunoglobulin gamma Fc receptor genes located on chromosome 1. This family member lacks the transmembrane and coiled-coiled domains found in other family members and is thought to be a pseudogene of Fc-gamma-receptor 1A. [provided by RefSeq, Apr 2009]
- clec-149 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including acquired immunodeficiency syndrome; bronchopulmonary dysplasia; and tuberculosis (multiple). Is an ortholog of human CD209 (CD209 molecule) and FCER2 (Fc epsilon receptor II).
- Fcgbp [Search on AGR]
Rattus norvegicus Predicted to be active in extracellular matrix and extracellular space. Orthologous to human FCGBP (Fc gamma binding protein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol.
- Fcgr2a [Search on AGR]
Rattus norvegicus Enables immunoglobulin receptor binding activity. Involved in several processes, including regulation of Fc receptor mediated stimulatory signaling pathway; regulation of antibody-dependent cellular cytotoxicity; and regulation of tumor necrosis factor production. Located in cell surface. Used to study crescentic glomerulonephritis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to human FCGR2A (Fc gamma receptor IIa); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; Leishmaniasis pathway; phagocytosis pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol.