- bark [Search on AGR]
Drosophila melanogaster bark beetle (bark) encodes a putative transmembrane scavenger receptor-like protein that is essential for the maturation of septate junctions (SJ). Loss of bark produces cell adhesion defects and mislocalization of SJ core complexes.
- pck [Search on AGR]
Drosophila melanogaster pickel (pck) encodes a transmembrane protein of the Claudin superfamily. It is part of the septate junction (SJ) core complex and essential for SJ morphogenesis and function. The transepithelial barrier function of epithelial tissues is affected in pck mutants.
- cht-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables chitinase activity. Involved in chitin catabolic process and response to fungus. Predicted to be located in extracellular region. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Is an ortholog of human CHIA (chitinase acidic).
- Chial1 [Search on AGR]
Rattus norvegicus Predicted to enable chitin binding activity and chitinase activity. Predicted to be involved in chitin catabolic process. Predicted to be located in membrane. Predicted to be active in extracellular region. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CHIA (chitinase acidic); INTERACTS WITH titanium dioxide.
- Chi3l3 [Search on AGR]
Rattus norvegicus Predicted to enable chitin binding activity. Predicted to be involved in chitin catabolic process. Predicted to be active in extracellular region. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CHIA (chitinase acidic); INTERACTS WITH bis(2-chloroethyl) sulfide; dioxygen; HU-308.
- Chia [Search on AGR]
Rattus norvegicus Enables chitinase activity. Involved in chitin catabolic process. Located in extracellular region. Biomarker of cryptococcosis and silicosis. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CHIA (chitinase acidic); PARTICIPATES IN amino sugar metabolic pathway; nucleotide sugar metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.