B0272.4

Caenorhabditis elegans

Predicted to enable delta(3)-delta(2)-enoyl-CoA isomerase activity. Predicted to be located in peroxisome. Expressed widely. Is an ortholog of several human genes including CDY1 (chromodomain Y-linked 1); CDY2A (chromodomain Y-linked 2A); and CDYL (chromodomain Y like).

npr-12

Caenorhabditis elegans

Predicted to enable neuropeptide Y receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in FLPL; FLPR; PVDL; and PVDR. Human ortholog(s) of this gene implicated in several diseases, including amphetamine abuse; cocaine abuse; and heroin dependence. Is an ortholog of human NPY1R (neuropeptide Y receptor Y1); NPY4R (neuropeptide Y receptor Y4); and NPY4R2 (neuropeptide Y receptor Y4-2).

Y53F4B.12

Caenorhabditis elegans

Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-arginine import across plasma membrane and L-ornithine transmembrane transport. Predicted to be located in plasma membrane.

cyy-1

Caenorhabditis elegans

Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity. Involved in negative regulation of synapse assembly; regulation of neuron remodeling; and regulation of terminal button organization. Located in axon and dendrite. Is an ortholog of human CCNY (cyclin Y) and CCNYL1 (cyclin Y like 1).

cey-4

Caenorhabditis elegans

Enables ribonucleoprotein complex binding activity. Predicted to be involved in regulation of gene expression. Part of ribonucleoprotein complex. Expressed in germ cell; germ line; and somatic cell. Is an ortholog of human YBX1 (Y-box binding protein 1) and YBX2 (Y-box binding protein 2).

F08F3.4

Caenorhabditis elegans

Predicted to enable L-threonine 3-dehydrogenase activity. Involved in innate immune response. Is an ortholog of human TDH (L-threonine dehydrogenase (pseudogene)).

npr-8

Caenorhabditis elegans

Predicted to enable neuropeptide Y receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane.

C15B12.1

Caenorhabditis elegans

Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be located in peroxisome. Is an ortholog of human PIPOX (pipecolic acid and sarcosine oxidase).

C15B12.8

Caenorhabditis elegans

Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be located in peroxisome. Is an ortholog of human PIPOX (pipecolic acid and sarcosine oxidase).

his-70

Caenorhabditis elegans

Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed in sperm. Is an ortholog of human H3Y1 (H3.Y histone 1) and H3Y2 (H3.Y histone 2).