Involved in negative regulation of vulval development and positive regulation of growth rate. Located in condensed chromosome and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and germ line. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 75. Is an ortholog of human TRRAP (transformation/transcription domain associated protein).
Enables polynucleotide 5'-phosphatase activity. Involved in polynucleotide 5' dephosphorylation and positive regulation of gene expression. Located in nucleus. Expressed in tail. Is an ortholog of human RNGTT (RNA guanylyltransferase and 5'-phosphatase).
Involved in several processes, including negative regulation of vulval development; protein stabilization; and vulval development. Located in nucleus. Expressed in gonad.
Enables histone H3K36 methyltransferase activity and histone H3K9 methyltransferase activity. Involved in several processes, including negative regulation of vulval development; regulation of gene expression; and vulval cell fate commitment. Located in cytoplasm. Expressed in hypodermis; intestine; muscle cell; neurons; and in male. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; autistic disorder; and prostate cancer. Is an ortholog of human SETDB1 (SET domain bifurcated histone lysine methyltransferase 1).