Enables cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of DNA-templated transcription; positive regulation of developmental process; and regulation of cell division. Located in nucleus. Expressed in several structures, including hypodermis; male-specific anatomical entity; neurons; somatic nervous system; and ventral cord blast cell. Is an ortholog of human HOXA5 (homeobox A5).
Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including clk-1; lin-39; and mir-34 based on RNA-seq and microarray studies.
Is affected by several genes including rsr-2; clk-1; and lin-39 based on RNA-seq; tiling array; and microarray studies. Is affected by estrogen and Acrylamide based on microarray studies.
Involved in defense response to Gram-positive bacterium and vulval development. Acts upstream of or within with a positive effect on cell fate specification. Located in cytoplasm and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; hermaphrodite distal tip cell; and vulval cell.
Enables neuropeptide activity. Involved in negative regulation of nematode larval development. Predicted to be located in extracellular space. Expressed in gonad; intestine; neurons; and pharynx.