Enables extracellularly glutamate-gated chloride channel activity. Involved in several processes, including locomotion involved in locomotory behavior; regulation of nematode pharyngeal pumping; and response to xenobiotic stimulus. Located in membrane. Expressed in head; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in hyperekplexia 1 and syndromic X-linked intellectual disability Pilorge type. Is an ortholog of human GLRA1 (glycine receptor alpha 1); GLRA2 (glycine receptor alpha 2); and GLRA3 (glycine receptor alpha 3).
Predicted to enable neurotransmitter receptor activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection; plasma membrane; and synapse. Predicted to be part of transmembrane transporter complex. Expressed in AIYL and AIYR.
Enables extracellularly glutamate-gated chloride channel activity; glutamate binding activity; and identical protein binding activity. Involved in chloride transmembrane transport; locomotion involved in locomotory behavior; and protein complex oligomerization. Located in plasma membrane. Expressed in body wall musculature; head neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in hyperekplexia 1; hyperekplexia 2; and syndromic X-linked intellectual disability Pilorge type. Is an ortholog of human GLRA2 (glycine receptor alpha 2) and GLRA3 (glycine receptor alpha 3).
Enables polynucleotide 5'-phosphatase activity. Involved in polynucleotide 5' dephosphorylation and positive regulation of gene expression. Located in nucleus. Expressed in tail. Is an ortholog of human RNGTT (RNA guanylyltransferase and 5'-phosphatase).
Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human ARL14EP (ADP ribosylation factor like GTPase 14 effector protein) and ARL14EPL (ADP ribosylation factor like GTPase 14 effector protein like).