Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Involved in polarity specification of anterior/posterior axis. Predicted to be located in cytoplasm; nucleus; and ribosome. Predicted to be part of ribonucleoprotein complex. Expressed in several structures, including hermaphrodite gonad; intestine; pharyngeal-intestinal valve; pharynx; and somatic nervous system. Human ortholog(s) of this gene implicated in colon carcinoma. Is an ortholog of human UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1).
Predicted to enable clathrin binding activity. Involved in receptor-mediated endocytosis. Predicted to be located in cytoplasm; intracellular membrane-bounded organelle; and vesicle. Human ortholog(s) of this gene implicated in Parkinson's disease 19A. Is an ortholog of human DNAJC6 (DnaJ heat shock protein family (Hsp40) member C6).