Enables peptide-O-fucosyltransferase activity. Involved in protein O-linked fucosylation. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Expressed in body wall musculature; hermaphrodite gonad; hypodermis; and somatic nervous system. Used to study Down syndrome. Is an ortholog of human POFUT2 (protein O-fucosyltransferase 2).
Predicted to be involved in Golgi to endosome transport and protein transport. Predicted to be located in endosome and trans-Golgi network. Expressed in head and tail. Used to study Down syndrome. Is an ortholog of human DOP1A (DOP1 leucine zipper like protein A) and DOP1B (DOP1 leucine zipper like protein B).
Predicted to enable clathrin binding activity. Involved in receptor-mediated endocytosis. Predicted to be located in cytoplasm; intracellular membrane-bounded organelle; and vesicle. Human ortholog(s) of this gene implicated in Parkinson's disease 19A. Is an ortholog of human DNAJC6 (DnaJ heat shock protein family (Hsp40) member C6).