Predicted to enable cytokine activity and phenylpyruvate tautomerase activity. Involved in regulation of lipid storage and regulation of peptide transport. Located in nucleus. Expressed in body wall musculature; pharyngeal muscle cell; and vulval muscle.
Predicted to enable cytokine activity and phenylpyruvate tautomerase activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cystic fibrosis; and lung disease (multiple). Is an ortholog of human MIF (macrophage migration inhibitory factor).
Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in L-leucine catabolic process and ketone body biosynthetic process. Used to study 3-hydroxy-3-methylglutaryl-CoA lyase deficiency. Human ortholog(s) of this gene implicated in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1).
Predicted to enable clathrin binding activity. Involved in receptor-mediated endocytosis. Predicted to be located in intracellular membrane-bounded organelle and vesicle. Human ortholog(s) of this gene implicated in Parkinson's disease 19A. Is an ortholog of human DNAJC6 (DnaJ heat shock protein family (Hsp40) member C6).