end-1

Caenorhabditis elegans

Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in endodermal cell fate specification and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in E; E lineage cell; Ea; and Ep.

end-3

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate specification and mesodermal cell fate specification. Located in nucleus. Expressed in E; E lineage cell; Ea; Ep; and intestine.

med-1

Caenorhabditis elegans

Enables sequence-specific DNA binding activity. Involved in endodermal cell fate specification and pharynx development. Located in nucleus. Expressed in several structures, including MSaaaap; MSaapap; MSappp; MSppapa; and MSppapp.

cids-1

Caenorhabditis elegans

Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Is an ortholog of human RPRD1A (regulation of nuclear pre-mRNA domain containing 1A).

T08D2.8

Caenorhabditis elegans

Predicted to enable microtubule plus end polymerase and microtubule plus-end binding activity. Predicted to be involved in establishment or maintenance of microtubule cytoskeleton polarity; microtubule polymerization; and spindle organization. Predicted to be located in intracellular non-membrane-bounded organelle and supramolecular complex.

cpf-1

Caenorhabditis elegans

Predicted to be involved in mRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage stimulating factor complex. Is an ortholog of human CSTF1 (cleavage stimulation factor subunit 1).

ptrn-1

Caenorhabditis elegans

Enables microtubule minus-end binding activity. Involved in cytoplasmic microtubule organization and nematode larval development. Located in microtubule minus-end. Expressed in hypodermis; intestine; nervous system; and pharynx. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Is an ortholog of human CAMSAP1 (calmodulin regulated spectrin associated protein 1); CAMSAP2 (calmodulin regulated spectrin associated protein family member 2); and CAMSAP3 (calmodulin regulated spectrin associated protein family member 3).

cids-2

Caenorhabditis elegans

Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Is an ortholog of human RPRD2 (regulation of nuclear pre-mRNA domain containing 2).

pfs-2

Caenorhabditis elegans

Predicted to be involved in mRNA 3'-end processing. Located in nuclear speck. Is an ortholog of human WDR33 (WD repeat domain 33).

dli-1

Caenorhabditis elegans

Predicted to enable dynein heavy chain binding activity. Involved in regulation of dendrite morphogenesis and retrograde axonal transport. Located in microtubule plus-end and neuron projection. Expressed in ciliated neurons; hypodermis; and pharynx. Is an ortholog of human DYNC1LI2 (dynein cytoplasmic 1 light intermediate chain 2).