brd-1

Caenorhabditis elegans

Enables ubiquitin protein ligase activity. Involved in DNA repair and protein ubiquitination. Part of BRCA1-BARD1 complex. Human ortholog(s) of this gene implicated in breast cancer and ovarian cancer. Is an ortholog of human BARD1 (BRCA1 associated RING domain 1).

brc-1

Caenorhabditis elegans

Enables ubiquitin protein ligase activity. Involved in several processes, including DNA repair; cellular response to ionizing radiation; and nuclear chromosome segregation. Part of BRCA1-BARD1 complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of human BRCA1 (BRCA1 DNA repair associated).

R12B2.6

Caenorhabditis elegans

Enriched in several structures, including ABplapaaaa; ABprapaaaa; Y cell; coelomocyte; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including brd-1; ints-4; and mir-34 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by atracurium; Oligosaccharides; and cadmium based on RNA-seq and microarray studies.

dnj-25

Caenorhabditis elegans

Predicted to enable clathrin binding activity. Involved in receptor-mediated endocytosis. Predicted to be located in cytoplasm; intracellular membrane-bounded organelle; and vesicle. Human ortholog(s) of this gene implicated in Parkinson's disease 19A. Is an ortholog of human DNAJC6 (DnaJ heat shock protein family (Hsp40) member C6).

C15F1.14

Caenorhabditis elegans

Is affected by cep-1; adr-1; and sftb-1 based on RNA-seq studies.

C17G10.14

Caenorhabditis elegans

Is affected by adr-1; etr-1; and ogt-1 based on RNA-seq studies.

C41C4.18

Caenorhabditis elegans

Is affected by prg-1; hsf-1; and glp-1 based on RNA-seq studies.

F18C5.15

Caenorhabditis elegans

Is affected by cep-1; dlc-1; and ogt-1 based on RNA-seq studies.

F26D11.15

Caenorhabditis elegans

Is affected by cep-1; dlc-1; and glp-1 based on RNA-seq studies.

R05F9.14

Caenorhabditis elegans

Is affected by adr-1; etr-1; and ogt-1 based on RNA-seq studies.