puf-7

Caenorhabditis elegans

Predicted to enable mRNA 3'-UTR binding activity. Involved in germ cell development. Predicted to be located in cytoplasm and nucleus.

puf-5

Caenorhabditis elegans

Enables mRNA 3'-UTR binding activity. Involved in positive regulation of embryonic development. Located in P granule. Expressed in germ line and oocyte.

puf-6

Caenorhabditis elegans

Predicted to enable mRNA 3'-UTR binding activity. Involved in germ cell development and negative regulation of cell population proliferation. Predicted to be located in cytoplasm and nucleus.

puf-9

Caenorhabditis elegans

Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in mRNA catabolic process and negative regulation of translation. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including HSN; gonad; ventral nerve cord; vulval muscle; and vulval precursor cell. Human ortholog(s) of this gene implicated in cerebellar ataxia type 47. Is an ortholog of human PUM2 (pumilio RNA binding family member 2).

R03G8.4

Caenorhabditis elegans

Is affected by several genes including cyc-1; hyl-2; and puf-8 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eight chemicals including methylmercury hydroxide; silicon dioxide nanoparticle; and Doxycycline based on RNA-seq and microarray studies.

puf-3

Caenorhabditis elegans

Enables mRNA 3'-UTR binding activity. Predicted to be involved in post-transcriptional regulation of gene expression. Predicted to be located in cytoplasm and nucleus. Expressed in germ line.

Y48B6A.17

Caenorhabditis elegans

Is affected by several genes including puf-8; npr-8; and ins-11 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies.

puf-8

Caenorhabditis elegans

Enables mRNA 3'-UTR binding activity. Involved in male meiotic nuclear division; negative regulation of MAPK cascade; and spermatogenesis. Located in P granule and nuclear periphery. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; germ line; and vulva. Used to study obesity. Human ortholog(s) of this gene implicated in cerebellar ataxia type 47. Is an ortholog of human PUM1 (pumilio RNA binding family member 1) and PUM2 (pumilio RNA binding family member 2).

H39E23.3

Caenorhabditis elegans

Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including puf-8; atp-2; and etr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; rotenone; and Ag nanoparticles based on microarray and RNA-seq studies.

F02H6.4

Caenorhabditis elegans

Enriched in cephalic sheath cell; germ line; and oocyte based on tiling array and RNA-seq studies. Is affected by several genes including cyc-1; puf-8; and numr-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; mianserin; and D-glucose based on microarray and RNA-seq studies.