Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in regulation of cell migration and regulation of egg-laying behavior. Located in extracellular space. Expressed in several structures, including M4 neuron; P5.p; P7.p; male-specific anatomical entity; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including germ cell cancer (multiple); hypogonadotropic hypogonadism (multiple); and prostate disease (multiple). Is an ortholog of human FGF18 (fibroblast growth factor 18) and FGF8 (fibroblast growth factor 8).
Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-activating dopamine receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in cytoplasm. Predicted to be part of heterotrimeric G-protein complex.
Enables protein kinase activity. Involved in several processes, including egg-laying behavior; muscle cell cellular homeostasis; and nematode larval development. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in head neurons; hypodermis; intestine; male sex myoblast; and vulval muscle. Used to study bone disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; bone disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human FGFR2 (fibroblast growth factor receptor 2).
Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi membrane. Is an ortholog of human B3GALT1 (beta-1,3-galactosyltransferase 1).
Predicted to enable interleukin-17 receptor activity. Involved in positive regulation of locomotion and response to oxygen levels. Located in plasma membrane. Part of receptor complex. Expressed in RMGL and RMGR. Human ortholog(s) of this gene implicated in immunodeficiency 51. Is an ortholog of human IL17RA (interleukin 17 receptor A) and IL17RB (interleukin 17 receptor B).
Predicted to enable G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and egg-laying behavior. Predicted to be located in axon; membrane; and somatodendritic compartment. Expressed in HSNL; HSNR; PVQL; PVQR; and vulva.