vg

Drosophila melanogaster

vestigial (vg) encodes a wing/haltere identity selector gene. It functions as a transcriptional activator when bound to the product of sd to direct wing specific gene expression and regulate cell proliferation. It also has a role in muscle specification.

Vgll1

Homo sapiens

The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. [provided by RefSeq, Sep 2009]

sd

Drosophila melanogaster

scalloped (sd) encodes a DNA binding protein of the TEAD class. It requires co-factor proteins ,such as the products of vg and yki, to act as a transcription factor, and is modified by Hippo and Wingless signalling. It is involved in wing and neuronal specification.